Code: BIOL-446
Semester: G
Course Type: Elective
ECTS units: 4
Hours per week: Theory - 2 hours

Instructor

Associate Professor: Ladoukakis Emmanuel
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Office phone number:  +30 2810 394067
Lab phone number:  +30 2810 394074

Description

Objectives of the course (preferably expressed in terms of learning outcomes and competences):  To understand the basic mechanisms which shape evolution of molecules

Course contents: Dynamics of mutations. Advantageous, deleterious and neutral mutations. Estimating the number of nucleotide substitutions between sequences. Rates and patterns of nucleotide substitutions. Increase of genetic information in genomes. Evolution by gene duplication and domain shuffling. Evolution by transposition and horizontal gene transfer. Concerted evolution of multigene families. Evolution of coding and non-coding genomic sequences. DNA polymorphism in populations. Molecular clocks. Molecular phylogenetics.