Code: BIOL-473
Semester: H (even calendar years)
Course Type: Elective
ECTS units: 4
Hours per week: Theory - 3 hours

Instructor

Professor: Spilianakis Charalampos
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Office phone number:  +30 2810 391163
Lab phone number:  +30 2810 391173

Description

Introduces fundamentals concepts in genome architecture and genomics including research approaches to uncover genetic variation and the relationship between genotype and phenotype. Prerequisite: BIOL207 – MOLECULAR BIOLOGY.

Contents

  • Mapping Genomes
  • Sequencing Genomes
  • Genome annotation
  • Identifying gene functions
  • Eukaryotic nuclear genomes
  • Genomes of prokaryotes and eukaryotic organelles
  • Viral genomes and mobile genetic elements
  • Accessing the genome
  • The role of DNA-binding proteins in genome expression
  • Transcriptomes
  • Proteomes
  • Genome expression in the context of cell and organism
  • How genomes evolve

Learning Outcomes

  • Knowledge and Understanding: All components of the course provide this to some degree but your lectures, in particular, offer an important framework upon which you can build attributes. This University considers itself to be a research-led institution and you will be exposed to cutting edge information and ideas as you progress through the course. In this course you will develop a comprehensive knowledge of genome structure, function and evolution, of tools to analyze genomic data and of methods for genetic manipulation.
  • Research and Enquiry: These skills are enhanced by encouraging further reading of books, research papers and electronic materials, to embellish your lecture and practical material.
  • Personal and Intellectual Autonomy: By reading and preparing materials for sessions, you will learn to synthesize your own views, develop reasoned arguments and refine scientific judgement. Such skills enhance your capacity for life-long and independent learning.
  • Communication: This is a key attribute of all scientists and it is therefore important that you develop skills to interact constructively with others and convey knowledgeable and balanced scientific views.

Personal Effectiveness: The ability to organize and summaries your thoughts and material in a flexible and accessible way are core features that are required for personal effectiveness. Planning, time management and reflection are central to this. Of course, these features also interlink with your personal and intellectual autonomy. By providing you with a timetable where key submission dates are highlighted, we are encouraging you to develop your effectiveness throughout the course. These same skills extend to other courses and also to your overall ability to maximize your achievement whilst at the University.