PHD:           1990, University of Crete

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Scientific interests

We use model gene networks in yeast cells to study a) the dynamics of basic transcriptional regulation, b) the molecular base of epigenetic inheritance of transcriptional states, and c) the mechanism(s) underlying age-related changes in cellular function and gene expression. Current projects include studies on global transcriptional co-activators and co-repressors, chromatin mediated transcriptional regulation, on molecular mechanism(s) underlying epigenetic transmission of cellular memory and studies on the asymmetric inheritance of damaged macromolecules upon cellular aging.

Recent publications

  • Zacharioudakis I., and D. Tzamarias  (2016). A novel CRE recombinase assay for quantification of GAL10-non coding RNA suppression on transcriptional leakage.  Biochem Biophys Res Commun. 473(4):1191-6.
  • Zacharioudakis I., Papagiannidis D., Gounalaki N., Stratidaki.I, Kafetzopoulos D.,  and  D. Tzamarias  (2017). Ras mutants enhance the ability of cells to anticipate future lethal stressors. Biochem Biophys Res Commun. 482(4):1278-1283.
  •  Zacharioudakis I., and D. Tzamarias (2017). Bimodal expression of yeast GAL genes is controlled by a long non-coding RNA and a bifunctional galactokinase.  Biochem Biophys Res Commun.  (17)30418-7.
  • Lytras G., Zacharioudakis I., and D. Tzamarias  (2017).  Asymmetric inheritance of the yeast small heat shock chaperon Hsp26 and its functional consequences.  Biochem Biophys Res Commun. pii: S0006-291X(17)31545-0. doi: 10.1016/j.bbrc.2017. 08.009.
  • Tartas A., Zarkadas C., Palaiomylitou M., Gounalaki N.,  Tzamarias D. and M. Vlassi  (2017).  Ssn6/Tup1 interaction: Role of the N-terminal glutamine-rich region of Ssn6.  PLOS ONE 12(10):e0186363.